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A multicolor panel of TALE-KRAB based transcriptional repressor vectors enabling knockdown of multiple gene targets

Stable and efficient knockdown of multiple gene targets is highly desirable for dissection of molecular pathways. Because it allows sequence-specific DNA binding, transcription activator-like effector (TALE) offers a new genetic perturbation technique that allows for gene-specific repression. Here,...

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Detalles Bibliográficos
Autores principales: Zhang, Zhonghui, Wu, Elise, Qian, Zhijian, Wu, Wen-Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256643/
https://www.ncbi.nlm.nih.gov/pubmed/25475013
http://dx.doi.org/10.1038/srep07338