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Systematic analysis of the in situ crosstalk of tyrosine modifications reveals no additional natural selection on multiply modified residues

Recent studies have indicated that different post-translational modifications (PTMs) synergistically orchestrate specific biological processes by crosstalks. However, the preference of the crosstalk among different PTMs and the evolutionary constraint on the PTM crosstalk need further dissections. I...

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Detalles Bibliográficos
Autores principales: Pan, Zhicheng, Liu, Zexian, Cheng, Han, Wang, Yongbo, Gao, Tianshun, Ullah, Shahid, Ren, Jian, Xue, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256647/
https://www.ncbi.nlm.nih.gov/pubmed/25476580
http://dx.doi.org/10.1038/srep07331