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Estimation of Epistatic Variance Components and Heritability in Founder Populations and Crosses

Genetic association studies have explained only a small proportion of the estimated heritability of complex traits, leaving the remaining heritability “missing.” Genetic interactions have been proposed as an explanation for this, because they lead to overestimates of the heritability and are hard to...

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Detalles Bibliográficos
Autores principales: Young, Alexander I., Durbin, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256760/
https://www.ncbi.nlm.nih.gov/pubmed/25326236
http://dx.doi.org/10.1534/genetics.114.170795