A Novel and Fast Approach for Population Structure Inference Using Kernel-PCA and Optimization

Population structure is a confounding factor in genome-wide association studies, increasing the rate of false positive associations. To correct for it, several model-based algorithms such as ADMIXTURE and STRUCTURE have been proposed. These tend to suffer from the fact that they have a considerable...

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Detalles Bibliográficos
Autores principales: Popescu, Andrei-Alin, Harper, Andrea L., Trick, Martin, Bancroft, Ian, Huber, Katharina T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256762/
https://www.ncbi.nlm.nih.gov/pubmed/25326237
http://dx.doi.org/10.1534/genetics.114.171314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256762/
https://www.ncbi.nlm.nih.gov/pubmed/25326237
http://dx.doi.org/10.1534/genetics.114.171314

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