Cargando…
A Novel and Fast Approach for Population Structure Inference Using Kernel-PCA and Optimization
Population structure is a confounding factor in genome-wide association studies, increasing the rate of false positive associations. To correct for it, several model-based algorithms such as ADMIXTURE and STRUCTURE have been proposed. These tend to suffer from the fact that they have a considerable...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Genetics Society of America
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256762/ https://www.ncbi.nlm.nih.gov/pubmed/25326237 http://dx.doi.org/10.1534/genetics.114.171314 |