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Arecoline induces TNF-alpha production and Zonula Occludens-1 redistribution in mouse Sertoli TM4 cells

BACKGROUND: Arecoline, a major alkaloid in Areca nut has the ability to induce oxidative stress. The effect of Areca nut, arecoline on reducing sperm quality and quantity were documented previously using several animal models. Junction disruption by down-regulation of the junction-adhesive protein v...

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Detalles Bibliográficos
Autores principales: Kuo, Tzer-Min, Luo, Shun-Yuan, Chiang, Shang-Lun, Lee, Chi-Pin, Liu, Yu-Fan, Chang, Jan-Gowth, Tsai, Ming-Hsui, Ko, Ying-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256803/
https://www.ncbi.nlm.nih.gov/pubmed/25200553
http://dx.doi.org/10.1186/s12929-014-0093-z