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Levels of human replication factor C4, a clamp loader, correlate with tumor progression and predict the prognosis for colorectal cancer

BACKGROUND: Human replication factor C4 (RFC4) is involved in DNA replication as a clamp loader and is aberrantly regulated across a range of cancers. The current study aimed to investigate the function of RFC4 in colorectal cancer (CRC). METHODS: The mRNA levels of RFC4 were assessed in 30 paired p...

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Detalles Bibliográficos
Autores principales: Xiang, Jun, Fang, Lekun, Luo, Yanxin, Yang, Zuli, Liao, Yi, Cui, Ji, Huang, Meijin, Yang, Zihuan, Huang, Yan, Fan, Xinjuan, Wang, Huashe, Wang, Lei, Peng, Junsheng, Wang, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256821/
https://www.ncbi.nlm.nih.gov/pubmed/25407051
http://dx.doi.org/10.1186/s12967-014-0320-0