Cargando…

Levels of human replication factor C4, a clamp loader, correlate with tumor progression and predict the prognosis for colorectal cancer

BACKGROUND: Human replication factor C4 (RFC4) is involved in DNA replication as a clamp loader and is aberrantly regulated across a range of cancers. The current study aimed to investigate the function of RFC4 in colorectal cancer (CRC). METHODS: The mRNA levels of RFC4 were assessed in 30 paired p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiang, Jun, Fang, Lekun, Luo, Yanxin, Yang, Zuli, Liao, Yi, Cui, Ji, Huang, Meijin, Yang, Zihuan, Huang, Yan, Fan, Xinjuan, Wang, Huashe, Wang, Lei, Peng, Junsheng, Wang, Jianping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256821/ https://www.ncbi.nlm.nih.gov/pubmed/25407051 http://dx.doi.org/10.1186/s12967-014-0320-0

Ejemplares similares

Clamp loader ATPases and the evolution of DNA replication machinery
por: Kelch, Brian A, et al.
Publicado: (2012)

The Role of Replication Clamp-Loader Protein HolC of Escherichia coli in Overcoming Replication/Transcription Conflicts
por: Cooper, Deani L., et al.
Publicado: (2021)

The Escherichia coli clamp loader rapidly remodels SSB on DNA to load clamps
por: Newcomb, Elijah S P, et al.
Publicado: (2022)

Eukaryotic clamp loaders and unloaders in the maintenance of genome stability
por: Lee, Kyoo-young, et al.
Publicado: (2020)

Insights into the structure and assembly of the Bacillus subtilis clamp-loader complex and its interaction with the replicative helicase
por: Afonso, José P., et al.
Publicado: (2013)

Expression of A disintegrin and metalloprotease 8 is associated with cell growth and poor survival in colorectal cancer
por: Yang, Zuli, et al.
Publicado: (2014)

The Escherichia coli Clamp Loader Can Actively Pry Open the β-Sliding Clamp
por: Paschall, Christopher O., et al.
Publicado: (2011)

Nuclear receptor binding protein 1 correlates with better prognosis and induces caspase-dependent intrinsic apoptosis through the JNK signalling pathway in colorectal cancer
por: Liao, Yi, et al.
Publicado: (2018)

Unexpected new insights into DNA clamp loaders: Eukaryotic clamp loaders contain a second DNA site for recessed 5′ ends that facilitates repair and signals DNA damage
por: Li, Huilin, et al.
Publicado: (2022)

The Elg1 Clamp Loader Plays a Role in Sister Chromatid Cohesion
por: Parnas, Oren, et al.
Publicado: (2009)

Characterization of subcellular localization of eukaryotic clamp loader/unloader and its regulatory mechanism
por: Park, Su Hyung, et al.
Publicado: (2021)

Biochemical Characterization of DNA Damage Checkpoint Complexes: Clamp Loader and Clamp Complexes with Specificity for 5′ Recessed DNA
por: Ellison, Viola, et al.
Publicado: (2003)

MutS functions as a clamp loader by positioning MutL on the DNA during mismatch repair
por: Yang, Xiao-Wen, et al.
Publicado: (2022)

NFκB1 and NFκBIA Polymorphisms Are Associated with Increased Risk for Sporadic Colorectal Cancer in a Southern Chinese Population
por: Song, Shunxin, et al.
Publicado: (2011)

Allosteric communication in DNA polymerase clamp loaders relies on a critical hydrogen-bonded junction
por: Subramanian, Subu, et al.
Publicado: (2021)

Genetic Analysis of DinG Family Helicase YoaA and Its Interaction with Replication Clamp Loader Protein HolC in Escherichia coli
por: Sutera, Vincent A., et al.
Publicado: (2021)

Conserved residues in the δ subunit help the E. coli clamp loader, γ complex, target primer-template DNA for clamp assembly
por: Chen, Siying, et al.
Publicado: (2008)

Human CTF18-RFC clamp-loader complexed with non-synthesising DNA polymerase ε efficiently loads the PCNA sliding clamp
por: Fujisawa, Ryo, et al.
Publicado: (2017)

Linkers and loaders /
por: Levine, John R.
Publicado: (2000)

Linkers and loaders
por: Levine, John R
Publicado: (2000)

Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader
por: Gaubitz, Christl, et al.
Publicado: (2022)

Connecting Replication and Repair: YoaA, a Helicase-Related Protein, Promotes Azidothymidine Tolerance through Association with Chi, an Accessory Clamp Loader Protein
por: Brown, Laura T., et al.
Publicado: (2015)

The novel long noncoding RNA u50535 promotes colorectal cancer growth and metastasis by regulating CCL20
por: Yu, Xihu, et al.
Publicado: (2018)

Overexpression of MEKK2 is associated with colorectal carcinogenesis
por: JIANG, LI, et al.
Publicado: (2013)

Structure of the human RAD17–RFC clamp loader and 9–1–1 checkpoint clamp bound to a dsDNA–ssDNA junction
por: Day, Matthew, et al.
Publicado: (2022)

Ctf18-RFC and DNA Pol ϵ form a stable leading strand polymerase/clamp loader complex required for normal and perturbed DNA replication
por: Stokes, Katy, et al.
Publicado: (2020)

The Ctf18RFC Clamp Loader Is Essential for Telomere Stability in Telomerase-Negative and mre11 Mutant Alleles
por: Gao, Honghai, et al.
Publicado: (2014)

Solution study of the Escherichia coli DNA polymerase III clamp loader reveals the location of the dynamic ψχ heterodimer
por: Tondnevis, Farzaneh, et al.
Publicado: (2015)

Effect of a Defective Clamp Loader Complex of DNA Polymerase III on Growth and SOS Response in Pseudomonas aeruginosa
por: Spinnato, Maria Concetta, et al.
Publicado: (2022)

AQP9-induced cell cycle arrest is associated with RAS activation and improves chemotherapy treatment efficacy in colorectal cancer
por: Huang, Dandan, et al.
Publicado: (2017)

BRCA2 Acts as RAD51 Loader to Facilitate Telomere Replication and Capping
por: Badie, Sophie, et al.
Publicado: (2010)

Viral hijacking of a replicative helicase loader and its implications for helicase loading control and phage replication
por: Hood, Iris V, et al.
Publicado: (2016)

Side loader with automatic guidance
por: CERN. Geneva. Super Proton Synchrotron Division (SPS)
Publicado: (1974)

Low expression of RecQ-like helicase 5 is associated with poor prognosis in patients with gastric cancer
por: Lin, Yijia, et al.
Publicado: (2020)

Division of Labor between PCNA Loaders in DNA Replication and Sister Chromatid Cohesion Establishment
por: Liu, Hon Wing, et al.
Publicado: (2020)

Hypothesis: bacterial clamp loader ATPase activation through DNA-dependent repositioning of the catalytic base and of a trans-acting catalytic threonine
por: Neuwald, Andrew F.
Publicado: (2006)

The interplay of primer-template DNA phosphorylation status and single-stranded DNA binding proteins in directing clamp loaders to the appropriate polarity of DNA
por: Hayner, Jaclyn N., et al.
Publicado: (2014)

Oracle SQL*Loader: the definitive guide
por: Gennick, Jonathan, et al.
Publicado: (2001)

Structure of the cohesin loader Scc2
por: Chao, William C. H., et al.
Publicado: (2017)

Fault Diagnosis of Loader Gearbox Based on an ICA and SVM Algorithm
por: Chen, Zhongxin, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_6kvcg8i2e7i1sl1d3op350g74h