Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets

BACKGROUND: Epigenetic factors regulate tissue-specific expression and X-chromosome inactivation. Previous studies have identified epigenetic differences between sexes in some human tissues. However, it is unclear whether epigenetic modifications contribute to sex-specific differences in insulin sec...

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Detalles Bibliográficos
Autores principales: Hall, Elin, Volkov, Petr, Dayeh, Tasnim, Esguerra, Jonathan Lou S, Salö, Sofia, Eliasson, Lena, Rönn, Tina, Bacos, Karl, Ling, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256841/
https://www.ncbi.nlm.nih.gov/pubmed/25517766
http://dx.doi.org/10.1186/s13059-014-0522-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256841/
https://www.ncbi.nlm.nih.gov/pubmed/25517766
http://dx.doi.org/10.1186/s13059-014-0522-z

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