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Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets

BACKGROUND: Epigenetic factors regulate tissue-specific expression and X-chromosome inactivation. Previous studies have identified epigenetic differences between sexes in some human tissues. However, it is unclear whether epigenetic modifications contribute to sex-specific differences in insulin sec...

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Detalles Bibliográficos
Autores principales:	Hall, Elin, Volkov, Petr, Dayeh, Tasnim, Esguerra, Jonathan Lou S, Salö, Sofia, Eliasson, Lena, Rönn, Tina, Bacos, Karl, Ling, Charlotte
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256841/ https://www.ncbi.nlm.nih.gov/pubmed/25517766 http://dx.doi.org/10.1186/s13059-014-0522-z

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