A phylogeny-based sampling strategy and power calculator informs genome-wide associations study design for microbial pathogens

Whole genome sequencing is increasingly used to study phenotypic variation among infectious pathogens and to evaluate their relative transmissibility, virulence, and immunogenicity. To date, relatively little has been published on how and how many pathogen strains should be selected for studies asso...

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Detalles Bibliográficos
Autores principales: Farhat, Maha R, Shapiro, B Jesse, Sheppard, Samuel K, Colijn, Caroline, Murray, Megan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256898/
https://www.ncbi.nlm.nih.gov/pubmed/25484920
http://dx.doi.org/10.1186/s13073-014-0101-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256898/
https://www.ncbi.nlm.nih.gov/pubmed/25484920
http://dx.doi.org/10.1186/s13073-014-0101-7

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