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A phylogeny-based sampling strategy and power calculator informs genome-wide associations study design for microbial pathogens
Whole genome sequencing is increasingly used to study phenotypic variation among infectious pathogens and to evaluate their relative transmissibility, virulence, and immunogenicity. To date, relatively little has been published on how and how many pathogen strains should be selected for studies asso...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256898/ https://www.ncbi.nlm.nih.gov/pubmed/25484920 http://dx.doi.org/10.1186/s13073-014-0101-7 |