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Recombinant Lactobacillus plantarum expressing and secreting heterologous oxalate decarboxylase prevents renal calcium oxalate stone deposition in experimental rats

BACKGROUND: Calcium oxalate (CaOx) is the major constituent of about 75% of all urinary stone and the secondary hyperoxaluria is a primary risk factor. Current treatment options for the patients with hyperoxaluria and CaOx stone diseases are limited. Oxalate degrading bacteria might have beneficial...

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Detalles Bibliográficos
Autores principales: Sasikumar, Ponnusamy, Gomathi, Sivasamy, Anbazhagan, Kolandaswamy, Abhishek, Albert, Paul, Eldho, Vasudevan, Varadaraj, Sasikumar, Sundaresan, Selvam, Govindan Sadasivam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256919/
https://www.ncbi.nlm.nih.gov/pubmed/25175550
http://dx.doi.org/10.1186/s12929-014-0086-y