Roxithromycin treatment inhibits TGF-β1-induced activation of ERK and AKT and down-regulation of Caveolin-1 in rat airway smooth muscle cells

BACKGROUND: Roxithromycin (RXM) has been widely used in asthma treatment; however, the mechanism has not been fully understood. The aim of our study was to investigate the underlying mechanism of RXM treatment in mediating the effect of transforming growth factor (TGF)-β1 on airway smooth muscle cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Dai, Yuanrong, Li, Fengqin, Wu, Liqin, Wang, Ruili, Li, Ping, Yan, Sunshun, Xu, Hui, Xia, Mengling, Bai, Chunxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256937/
https://www.ncbi.nlm.nih.gov/pubmed/25109503
http://dx.doi.org/10.1186/s12931-014-0096-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256937/
https://www.ncbi.nlm.nih.gov/pubmed/25109503
http://dx.doi.org/10.1186/s12931-014-0096-z

Ejemplares similares