Deficiency of the bone mineralization inhibitor NPP1 protects mice against obesity and diabetes

The emergence of bone as an endocrine regulator has prompted a re-evaluation of the role of bone mineralization factors in the development of metabolic disease. Ectonucleotide pyrophosphatase/phosphodiesterase-1 (NPP1) controls bone mineralization through the generation of pyrophosphate, and levels...

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Detalles Bibliográficos
Autores principales: Huesa, Carmen, Zhu, Dongxing, Glover, James D., Ferron, Mathieu, Karsenty, Gerard, Milne, Elspeth M., Millan, José Luis, Ahmed, S. Faisal, Farquharson, Colin, Morton, Nicholas M., MacRae, Vicky E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257003/
https://www.ncbi.nlm.nih.gov/pubmed/25368121
http://dx.doi.org/10.1242/dmm.017905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257003/
https://www.ncbi.nlm.nih.gov/pubmed/25368121
http://dx.doi.org/10.1242/dmm.017905

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