Injectable long-acting systems for Radix Ophiopogonis polysaccharide based on mono-PEGylation and in situ formation of a PLGA depot

BACKGROUND: Radix Ophiopogonis polysaccharide (ROP), a highly hydrophilic macromolecule, has a unique anti-ischemic action in the myocardium. One of the main problems with its use is its relatively short half-life in vivo. To solve this problem, injectable long-acting drug delivery systems, which co...

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Detalles Bibliográficos
Autores principales: Shi, XiaoLi, Lin, Xiao, Zheng, XiangWei, Feng, Yi, Shen, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257019/
https://www.ncbi.nlm.nih.gov/pubmed/25489243
http://dx.doi.org/10.2147/IJN.S71819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257019/
https://www.ncbi.nlm.nih.gov/pubmed/25489243
http://dx.doi.org/10.2147/IJN.S71819

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