Antifungal amphiphilic aminoglycoside K20: bioactivities and mechanism of action

K20 is a novel amphiphilic antifungal aminoglycoside that is synthetically derived from the antibiotic kanamycin A. Reported here are investigations of K20′s antimicrobial activities, cytotoxicity, and fungicidal mechanism of action. In vitro growth inhibitory activities against a variety of human a...

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Detalles Bibliográficos
Autores principales: Shrestha, Sanjib K., Chang, Cheng-Wei T., Meissner, Nicole, Oblad, John, Shrestha, Jaya P., Sorensen, Kevin N., Grilley, Michelle M., Takemoto, Jon Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257101/
https://www.ncbi.nlm.nih.gov/pubmed/25538692
http://dx.doi.org/10.3389/fmicb.2014.00671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257101/
https://www.ncbi.nlm.nih.gov/pubmed/25538692
http://dx.doi.org/10.3389/fmicb.2014.00671

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