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Antifungal amphiphilic aminoglycoside K20: bioactivities and mechanism of action
K20 is a novel amphiphilic antifungal aminoglycoside that is synthetically derived from the antibiotic kanamycin A. Reported here are investigations of K20′s antimicrobial activities, cytotoxicity, and fungicidal mechanism of action. In vitro growth inhibitory activities against a variety of human a...
Autores principales: | Shrestha, Sanjib K., Chang, Cheng-Wei T., Meissner, Nicole, Oblad, John, Shrestha, Jaya P., Sorensen, Kevin N., Grilley, Michelle M., Takemoto, Jon Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257101/ https://www.ncbi.nlm.nih.gov/pubmed/25538692 http://dx.doi.org/10.3389/fmicb.2014.00671 |
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