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Crystal structure of 9-(4-bromobutyl)-9H-fluorene-9-carboxylic acid
The title compound, C(18)H(17)BrO(2), is a key intermediate in the synthesis of lomitapide mesylate, a microsomal triglyceride transfer protein inhibitor. Its asymmetric unit contains two independent molecules with slightly different conformations; the mean planes of the 4-bromobutyl and carboxyl...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257222/ https://www.ncbi.nlm.nih.gov/pubmed/25484705 http://dx.doi.org/10.1107/S1600536814019564 |