Exposure to inflammatory cytokines selectively limits GM-CSF production by induced T regulatory cells

Interest in manipulating the immunosuppressive powers of Foxp3-expressing T regulatory cells as an immunotherapy has been tempered by their reported ability to produce proinflammatory cytokines when manipulated in vitro, or in vivo. Understanding processes that can limit this potentially deleterious...

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Detalles Bibliográficos
Autores principales: Reynolds, Ben C, Turner, Darryl G, McPherson, Rhoanne C, Prendergast, Catriona T, Phelps, Richard G, Turner, Neil A, O'Connor, Richard A, Anderton, Stephen M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Immunomodulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257504/
https://www.ncbi.nlm.nih.gov/pubmed/25168419
http://dx.doi.org/10.1002/eji.201444687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257504/
https://www.ncbi.nlm.nih.gov/pubmed/25168419
http://dx.doi.org/10.1002/eji.201444687

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