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S-Nitrosoglutathione Accelerates Recovery from 5-Fluorouracil-Induced Oral Mucositis

INTRODUCTION: Mucositis induced by anti-neoplastic drugs is an important, dose-limiting and costly side-effect of cancer therapy. AIM: To evaluate the effect of the topical application of S-nitrosoglutathione (GSNO), a nitric oxide donor, on 5-fluorouracil (5-FU)-induced oral mucositis in hamsters....

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Detalles Bibliográficos
Autores principales: Skeff, Maria Adriana, Brito, Gerly A. C., de Oliveira, Marcelo G., Braga, Cintia M., Cavalcante, Matheus M., Baldim, Victor, Holanda-Afonso, Rosenilde C., Silva-Boghossian, Carina M., Colombo, Ana Paula, Ribeiro, Ronaldo A., Moura-Neto, Vivaldo, Leitão, Renata F. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257535/
https://www.ncbi.nlm.nih.gov/pubmed/25478918
http://dx.doi.org/10.1371/journal.pone.0113378