Cargando…

Dynein Function and Protein Clearance Changes in Tumor Cells Induced by a Kunitz-Type Molecule, Amblyomin-X

Amblyomin-X is a Kunitz-type recombinant protein identified from the transcriptome of the salivary glands of the tick Amblyomma cajennense and has anti-coagulant and antitumoral activity. The supposed primary target of this molecule is the proteasome system. Herein, we elucidated intracellular event...

Descripción completa

Detalles Bibliográficos
Autores principales: Pacheco, Mario T. F., Berra, Carolina M., Morais, Kátia L. P., Sciani, Juliana M., Branco, Vania G., Bosch, Rosemary V., Chudzinski-Tavassi, Ana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257547/
https://www.ncbi.nlm.nih.gov/pubmed/25479096
http://dx.doi.org/10.1371/journal.pone.0111907