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Extracellular and Intracellular Mechanisms of Mechanotransduction in Three-Dimensionally Embedded Rat Chondrocytes

PURPOSE: Articular cartilage homeostasis involves modulation of chondrocyte matrix synthesis in response to mechanical stress (MS). We studied extracellular and intracellular mechanotransduction pathways mediating this response. METHODS: We first confirmed rapid up-regulation of the putative chondro...

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Detalles Bibliográficos
Autores principales: Shioji, Suguru, Imai, Shinji, Ando, Kosei, Kumagai, Kousuke, Matsusue, Yoshitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257595/
https://www.ncbi.nlm.nih.gov/pubmed/25479057
http://dx.doi.org/10.1371/journal.pone.0114327