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Extracellular and Intracellular Mechanisms of Mechanotransduction in Three-Dimensionally Embedded Rat Chondrocytes
PURPOSE: Articular cartilage homeostasis involves modulation of chondrocyte matrix synthesis in response to mechanical stress (MS). We studied extracellular and intracellular mechanotransduction pathways mediating this response. METHODS: We first confirmed rapid up-regulation of the putative chondro...
Autores principales: | Shioji, Suguru, Imai, Shinji, Ando, Kosei, Kumagai, Kousuke, Matsusue, Yoshitaka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257595/ https://www.ncbi.nlm.nih.gov/pubmed/25479057 http://dx.doi.org/10.1371/journal.pone.0114327 |
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