Structures of Plasmodium vivax serine hydroxymethyltransferase: implications for ligand-binding specificity and functional control

Plasmodium parasites, the causative agent of malaria, rely heavily on de novo folate biosynthesis, and the enzymes in this pathway have therefore been explored extensively for antimalarial development. Serine hydroxymethyltransferase (SHMT) from Plasmodium spp., an enzyme involved in folate recyclin...

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Detalles Bibliográficos
Autores principales: Chitnumsub, Penchit, Jaruwat, Aritsara, Riangrungroj, Pinpunya, Ittarat, Wanwipa, Noytanom, Krittikar, Oonanant, Worrapoj, Vanichthanankul, Jarunee, Chuankhayan, Phimonphan, Maenpuen, Somchart, Chen, Chun-Jung, Chaiyen, Pimchai, Yuthavong, Yongyuth, Leartsakulpanich, Ubolsree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257618/
https://www.ncbi.nlm.nih.gov/pubmed/25478836
http://dx.doi.org/10.1107/S1399004714023128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257618/
https://www.ncbi.nlm.nih.gov/pubmed/25478836
http://dx.doi.org/10.1107/S1399004714023128

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