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IL-6 Stimulates Intestinal Epithelial Proliferation and Repair after Injury

IL-6 is a pleiotropic cytokine often associated with inflammation. Inhibition of this pathway has led to successful treatment of rheumatoid arthritis, but one unforeseen potential complication of anti-IL-6 therapy is bowel perforation. Within the intestine, IL-6 has been shown to prevent epithelial...

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Detalles Bibliográficos
Autores principales: Kuhn, Kristine A., Manieri, Nicholas A., Liu, Ta-Chiang, Stappenbeck, Thaddeus S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257684/
https://www.ncbi.nlm.nih.gov/pubmed/25478789
http://dx.doi.org/10.1371/journal.pone.0114195