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MTM-6, a Phosphoinositide Phosphatase, is Required to Promote Synapse Formation in Caenorhabditis elegans

Forming the proper number of synapses is crucial for normal neuronal development. We found that loss of function of the phosphoinositide phosphatase mtm-6 results in a reduction in the number of synaptic puncta. The reduction in synapses is partially the result of MTM-6 regulation of the secretion o...

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Detalles Bibliográficos
Autores principales: Ericson, Vivian R., Spilker, Kerri A., Tugizova, Madina S., Shen, Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257696/
https://www.ncbi.nlm.nih.gov/pubmed/25479419
http://dx.doi.org/10.1371/journal.pone.0114501