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MTM-6, a Phosphoinositide Phosphatase, is Required to Promote Synapse Formation in Caenorhabditis elegans
Forming the proper number of synapses is crucial for normal neuronal development. We found that loss of function of the phosphoinositide phosphatase mtm-6 results in a reduction in the number of synaptic puncta. The reduction in synapses is partially the result of MTM-6 regulation of the secretion o...
Autores principales: | Ericson, Vivian R., Spilker, Kerri A., Tugizova, Madina S., Shen, Kang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257696/ https://www.ncbi.nlm.nih.gov/pubmed/25479419 http://dx.doi.org/10.1371/journal.pone.0114501 |
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