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An anti-angiogenic isoform of VEGF-A contributes to impaired vascularization in peripheral artery disease
Peripheral artery disease (PAD) generates tissue ischemia through arterial occlusions and insufficient collateral vessel formation. Vascular insufficiency in PAD occurs despite higher circulating levels of vascular endothelial growth factor A (VEGF-A),(1,2) a key regulator of angiogenesis. Here, we...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257756/ https://www.ncbi.nlm.nih.gov/pubmed/25362254 http://dx.doi.org/10.1038/nm.3703 |