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Variably Protease-Sensitive Prionopathy, a Unique Prion Variant with Inefficient Transmission Properties

Variably protease-sensitive prionopathy (VPSPr) can occur in persons of all codon 129 genotypes in the human prion protein gene (PRNP) and is characterized by a unique biochemical profile when compared with other human prion diseases. We investigated transmission properties of VPSPr by inoculating t...

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Detalles Bibliográficos
Autores principales: Diack, Abigail B., Ritchie, Diane L., Peden, Alexander H., Brown, Deborah, Boyle, Aileen, Morabito, Laura, Maclennan, David, Burgoyne, Paul, Jansen, Casper, Knight, Richard S., Piccardo, Pedro, Ironside, James W., Manson, Jean C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257789/
https://www.ncbi.nlm.nih.gov/pubmed/25418327
http://dx.doi.org/10.3201/eid2012.140214