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Adenosine kinase, glutamine synthetase and EAAT2 as gene therapy targets for temporal lobe epilepsy
Astrocytes are an attractive cell target for gene therapy but the validation of new therapeutic candidates is needed. We determined whether adeno-associated viral (AAV) vector-mediated overexpression of glutamine synthetase (GS) or excitatory amino acid transporter 2 (EAAT2), or expression of microR...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257851/ https://www.ncbi.nlm.nih.gov/pubmed/25231174 http://dx.doi.org/10.1038/gt.2014.82 |