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Narrowing the localization of the region breakpoint in most frequent Robertsonian translocations

Despite that Robertsonian translocations (ROBs) are the most common chromosomal rearrangements in humans (1/1000 individuals), an exact breakpoint and the molecular mechanisms leading to their formation are still not well known. This is partly due to the fact that Human Genome Project did not provid...

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Detalles Bibliográficos
Autores principales: Jarmuz-Szymczak, Malgorzata, Janiszewska, Joanna, Szyfter, Krzysztof, Shaffer, Lisa G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257996/
https://www.ncbi.nlm.nih.gov/pubmed/25179263
http://dx.doi.org/10.1007/s10577-014-9439-3