Purified anti-CD3 × anti-HER2 bispecific antibody potentiates cytokine-induced killer cells of poor spontaneous cytotoxicity against breast cancer cells

BACKGROUND: Chemical crosslinking is the most straightforward method to produce bispecific antibodies (BsAb) for arming ex vivo activated cytotoxic T lymphocytes. However, heterogeneous polymers are produced by chemical crosslinking. Currently, it is not known under what circumstances or to what ext...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Qingzhong, Zhang, Haisong, Wang, Youzhao, Ting, Hong Hoi, Yu, Wenhua, Cao, Xuetao, Ge, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258008/
https://www.ncbi.nlm.nih.gov/pubmed/25485089
http://dx.doi.org/10.1186/2045-3701-4-70

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258008/
https://www.ncbi.nlm.nih.gov/pubmed/25485089
http://dx.doi.org/10.1186/2045-3701-4-70

Ejemplares similares