Ring finger protein20 regulates hepatic lipid metabolism through protein kinase A-dependent sterol regulatory element binding protein1c degradation

Sterol regulatory element binding protein1c (SREBP1c) is a key transcription factor for de novo lipogenesis during the postprandial state. During nutritional deprivation, hepatic SREBP1c is rapidly suppressed by fasting signals to prevent lipogenic pathways. However, the molecular mechanisms that co...

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Detalles Bibliográficos
Autores principales: Lee, Jae Ho, Lee, Gha Young, Jang, Hagoon, Choe, Sung Sik, Koo, Seung-Hoi, Kim, Jae Bum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Steatohepatitis/Metabolic Liver Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258077/
https://www.ncbi.nlm.nih.gov/pubmed/24425205
http://dx.doi.org/10.1002/hep.27011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258077/
https://www.ncbi.nlm.nih.gov/pubmed/24425205
http://dx.doi.org/10.1002/hep.27011

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