Survivin Modulates Genes with Divergent Molecular Functions and Regulates Proliferation of Hematopoietic Stem Cells through Evi-1

The inhibitor of apoptosis protein Survivin regulates hematopoiesis, although its mechanisms of regulation of hematopoietic stem cells (HSCs) remain largely unknown. While investigating conditional Survivin deletion in mice, we found that Survivin was highly expressed in phenotypically defined HSCs...

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Detalles Bibliográficos
Autores principales: Fukuda, Seiji, Hoggatt, Jonathan, Singh, Pratibha, Abe, Mariko, Speth, Jennifer M., Hu, Peirong, Conway, Edward M., Nucifora, Giuseppina, Yamaguchi, Seiji, Pelus, Louis M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258188/
https://www.ncbi.nlm.nih.gov/pubmed/24903482
http://dx.doi.org/10.1038/leu.2014.183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258188/
https://www.ncbi.nlm.nih.gov/pubmed/24903482
http://dx.doi.org/10.1038/leu.2014.183

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