Calmodulin antagonists induce cell cycle arrest and apoptosis in vitro and inhibit tumor growth in vivo in human multiple myeloma

BACKGROUND: Human multiple myeloma (MM) is an incurable hematological malignancy for which novel therapeutic agents are needed. Calmodulin (CaM) antagonists have been reported to induce apoptosis and inhibit tumor cell invasion and metastasis in various tumor models. However, the antitumor effects o...

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Detalles Bibliográficos
Autores principales: Yokokura, Shigeyuki, Yurimoto, Saki, Matsuoka, Akihito, Imataki, Osamu, Dobashi, Hiroaki, Bandoh, Shuji, Matsunaga, Takuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258255/
https://www.ncbi.nlm.nih.gov/pubmed/25424011
http://dx.doi.org/10.1186/1471-2407-14-882

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258255/
https://www.ncbi.nlm.nih.gov/pubmed/25424011
http://dx.doi.org/10.1186/1471-2407-14-882

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