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A global assessment of cancer genomic alterations in epigenetic mechanisms

BACKGROUND: The notion that epigenetic mechanisms may be central to cancer initiation and progression is supported by recent next-generation sequencing efforts revealing that genes involved in chromatin-mediated signaling are recurrently mutated in cancer patients. RESULTS: Here, we analyze mutation...

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Detalles Bibliográficos
Autores principales: Shah, Muhammad A, Denton, Emily L, Arrowsmith, Cheryl H, Lupien, Mathieu, Schapira, Matthieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258301/
https://www.ncbi.nlm.nih.gov/pubmed/25484917
http://dx.doi.org/10.1186/1756-8935-7-29