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mTOR Signaling in Protein Translation Regulation: Implications in Cancer Genesis and Therapeutic Interventions
mTOR is a central nutrient sensor that signals a cell to grow and proliferate. Through distinct protein complexes it regulates different levels of available cellular energy substrates required for cell growth. One of the important functions of the complex is to maintain available amino acid pool by...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258317/ https://www.ncbi.nlm.nih.gov/pubmed/25505994 http://dx.doi.org/10.1155/2014/686984 |