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mTOR Signaling in Protein Translation Regulation: Implications in Cancer Genesis and Therapeutic Interventions

mTOR is a central nutrient sensor that signals a cell to grow and proliferate. Through distinct protein complexes it regulates different levels of available cellular energy substrates required for cell growth. One of the important functions of the complex is to maintain available amino acid pool by...

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Detalles Bibliográficos
Autores principales: Showkat, Mehvish, Beigh, Mushtaq A., Andrabi, Khurshid I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258317/
https://www.ncbi.nlm.nih.gov/pubmed/25505994
http://dx.doi.org/10.1155/2014/686984