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Myeloid-Derived Suppressor Cells as Therapeutic Target in Hematological Malignancies

Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of immature myeloid cells that accumulate during pathological conditions such as cancer and are associated with a poor clinical outcome. MDSC expansion hampers the host anti-tumor immune response by inhibition of T cell prolifera...

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Detalles Bibliográficos
Autores principales: De Veirman, Kim, Van Valckenborgh, Els, Lahmar, Qods, Geeraerts, Xenia, De Bruyne, Elke, Menu, Eline, Van Riet, Ivan, Vanderkerken, Karin, Van Ginderachter, Jo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258607/
https://www.ncbi.nlm.nih.gov/pubmed/25538893
http://dx.doi.org/10.3389/fonc.2014.00349