Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts

We compared mouse embryonic stem (ES) cells and fibroblasts (MEFs) for their ability to metabolically activate the environmental carcinogens benzo[a]pyrene (BaP), 3-nitrobenzanthrone (3-NBA) and aristolochic acid I (AAI), measuring DNA adduct formation by (32)P-postlabelling and expression of xenobi...

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Detalles Bibliográficos
Autores principales: Krais, Annette M., Mühlbauer, Karl-Rudolf, Kucab, Jill E., Chinbuah, Helena, Cornelius, Michael G., Wei, Quan-Xiang, Hollstein, Monica, Phillips, David H., Arlt, Volker M., Schmeiser, Heinz H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258613/
https://www.ncbi.nlm.nih.gov/pubmed/25230394
http://dx.doi.org/10.1016/j.tiv.2014.09.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258613/
https://www.ncbi.nlm.nih.gov/pubmed/25230394
http://dx.doi.org/10.1016/j.tiv.2014.09.004

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