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Mutations of epigenetic regulatory genes are common in thymic carcinomas

Genetic alterations and etiology of thymic epithelial tumors (TETs) are largely unknown, hampering the development of effective targeted therapies for patients with TETs. Here TETs of advanced-stage patients enrolled in a clinical trial of molecularly-guided targeted therapies were employed for targ...

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Detalles Bibliográficos
Autores principales: Wang, Yisong, Thomas, Anish, Lau, Christopher, Rajan, Arun, Zhu, Yuelin, Killian, J. Keith, Petrini, Iacopo, Pham, Trung, Morrow, Betsy, Zhong, Xiaogang, Meltzer, Paul S., Giaccone, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258655/
https://www.ncbi.nlm.nih.gov/pubmed/25482724
http://dx.doi.org/10.1038/srep07336