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Predicting expression: the complementary power of histone modification and transcription factor binding data

BACKGROUND: Transcription factors (TFs) and histone modifications (HMs) play critical roles in gene expression by regulating mRNA transcription. Modelling frameworks have been developed to integrate high-throughput omics data, with the aim of elucidating the regulatory logic that results from the in...

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Detalles Bibliográficos
Autores principales: Budden, David M, Hurley, Daniel G, Cursons, Joseph, Markham, John F, Davis, Melissa J, Crampin, Edmund J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258808/
https://www.ncbi.nlm.nih.gov/pubmed/25489339
http://dx.doi.org/10.1186/1756-8935-7-36