Megakaryocytes regulate hematopoietic stem cell quiescence via Cxcl4 secretion

In the bone marrow (BM), hematopoietic stem cells (HSCs) lodge in specialized microenvironments that tightly control their proliferative state to adapt to the varying needs for replenishment of blood cells while also preventing exhaustion(1). All putative niche cells suggested thus far have a non-he...

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Detalles Bibliográficos
Autores principales: Bruns, Ingmar, Lucas, Daniel, Pinho, Sandra, Ahmed, Jalal, Lambert, Michele P., Kunisaki, Yuya, Scheiermann, Christoph, Schiff, Lauren, Poncz, Mortimer, Bergman, Aviv, Frenette, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258871/
https://www.ncbi.nlm.nih.gov/pubmed/25326802
http://dx.doi.org/10.1038/nm.3707

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258871/
https://www.ncbi.nlm.nih.gov/pubmed/25326802
http://dx.doi.org/10.1038/nm.3707

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