Cargando…
Overexpression of E2F1 in human gastric carcinoma is involved in anti-cancer drug resistance
BACKGROUND: Routine chemotherapy often cannot achieve good therapeutic effects because of multidrug resistance (MDR). MDR is frequently caused by the elevated expression of the MDR1 gene encoding P-glycoprotein (P-gp). E2F1 is a frequently overexpressed protein in human tumor cells that increases th...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258940/ https://www.ncbi.nlm.nih.gov/pubmed/25466554 http://dx.doi.org/10.1186/1471-2407-14-904 |