Overexpression of E2F1 in human gastric carcinoma is involved in anti-cancer drug resistance

BACKGROUND: Routine chemotherapy often cannot achieve good therapeutic effects because of multidrug resistance (MDR). MDR is frequently caused by the elevated expression of the MDR1 gene encoding P-glycoprotein (P-gp). E2F1 is a frequently overexpressed protein in human tumor cells that increases th...

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Detalles Bibliográficos
Autores principales: Yan, Lin-Hai, Wei, Wei-Yuan, Cao, Wen-Long, Zhang, Xiao-Shi, Xie, Yu-Bo, Xiao, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258940/
https://www.ncbi.nlm.nih.gov/pubmed/25466554
http://dx.doi.org/10.1186/1471-2407-14-904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258940/
https://www.ncbi.nlm.nih.gov/pubmed/25466554
http://dx.doi.org/10.1186/1471-2407-14-904

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