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Uncovering Global SUMOylation Signaling Networks in a Site-Specific Manner

SUMOylation is a reversible post-translational modification essential for genome stability. Using high-resolution mass spectrometry, we have studied global SUMOylation in human cells and in a site-specific manner, identifying a total of over 4,300 SUMOylation sites in over 1,600 proteins. Moreover,...

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Detalles Bibliográficos
Autores principales: Hendriks, Ivo A., D’Souza, Rochelle C.J., Yang, Bing, Verlaan-de Vries, Matty, Mann, Matthias, Vertegaal, Alfred C.O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259010/
https://www.ncbi.nlm.nih.gov/pubmed/25218447
http://dx.doi.org/10.1038/nsmb.2890