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Design of DNA Pooling to Allow Incorporation of Covariates in Rare Variants Analysis
BACKGROUND: Rapid advances in next-generation sequencing technologies facilitate genetic association studies of an increasingly wide array of rare variants. To capture the rare or less common variants, a large number of individuals will be needed. However, the cost of a large scale study using whole...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259344/ https://www.ncbi.nlm.nih.gov/pubmed/25485788 http://dx.doi.org/10.1371/journal.pone.0114523 |