CRISPR Reveals a Distal Super-Enhancer Required for Sox2 Expression in Mouse Embryonic Stem Cells

The pluripotency of embryonic stem cells (ESCs) is maintained by a small group of master transcription factors including Oct4, Sox2 and Nanog. These core factors form a regulatory circuit controlling the transcription of a number of pluripotency factors including themselves. Although previous studie...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yan, Rivera, Chloe M., Ishii, Haruhiko, Jin, Fulai, Selvaraj, Siddarth, Lee, Ah Young, Dixon, Jesse R., Ren, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259346/
https://www.ncbi.nlm.nih.gov/pubmed/25486255
http://dx.doi.org/10.1371/journal.pone.0114485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259346/
https://www.ncbi.nlm.nih.gov/pubmed/25486255
http://dx.doi.org/10.1371/journal.pone.0114485

Ejemplares similares