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Fasciola hepatica Kunitz Type Molecule Decreases Dendritic Cell Activation and Their Ability to Induce Inflammatory Responses

The complete repertoire of proteins with immunomodulatory activity in Fasciola hepatica (Fh) has not yet been fully described. Here, we demonstrated that Fh total extract (TE) reduced LPS-induced DC maturation, and the DC ability to induce allogeneic responses. After TE fractionating, a fraction low...

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Detalles Bibliográficos
Autores principales: Falcón, Cristian R., Masih, Diana, Gatti, Gerardo, Sanchez, María Cecilia, Motrán, Claudia C., Cervi, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259355/
https://www.ncbi.nlm.nih.gov/pubmed/25486609
http://dx.doi.org/10.1371/journal.pone.0114505