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Functional Characterization of Nuclear Localization and Export Signals in Hepatitis C Virus Proteins and Their Role in the Membranous Web

The hepatitis C virus (HCV) is a positive strand RNA virus of the Flavivirus family that replicates in the cytoplasm of infected hepatocytes. Previously, several nuclear localization signals (NLS) and nuclear export signals (NES) have been identified in HCV proteins, however, there is little evidenc...

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Detalles Bibliográficos
Autores principales: Levin, Aviad, Neufeldt, Christopher J., Pang, Daniel, Wilson, Kristen, Loewen-Dobler, Darci, Joyce, Michael A., Wozniak, Richard W., Tyrrell, D. Lorne J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259358/
https://www.ncbi.nlm.nih.gov/pubmed/25485706
http://dx.doi.org/10.1371/journal.pone.0114629